Apoptosis description

Apoptosis is programmed cell death of individual cells. Apoptosis is an active cellular process which involves genes, activation of enzymes, signalling, and DNA fragmentation. Studies revealed that most of the genes and proteins needed to operate in apoptosis already exist in cells and thus indicates that apoptosis is cell suicide. Unlike necrotic cells, apoptotic cells do not induce an inflammatory response but are targets for phagocytosis by macrophages. Failure of cells to undergo apoptosis at a normal rate most likely contributes to the pathogenesis of many malignancies or ageing related diseases.

 
Cell- and tissue damage » Apoptosis Quantity Application Cat #
Collagen II, Mouse, mAb CIIC1 0.5 mg F FS IA P HM1062-FS
Collagen II, Mouse, mAb M2139 0.5 mg F FS IA P HM1063-FS
TIM-4, Mouse, mAb Kat5-18 0.5 mg FC FS IA IF HM1111-FS
Beta2-adrenoceptor, Human, mAb 6H8 100 µg FC FS IA HM2238
Apoptotic Neutrophils, Human, mAb BOB93 100 µg FC W HM2154
Apoptotic Neutrophils, Human, mAb BOB93, biotinylated 50 µg FC W HM2154BT
Apoptotic Neutrophils, Human, mAb BOB93, FITC 100 µg FC W HM2154F
Collagen II, Mouse, mAb CIIC1 100 µg F FS IA P HM1062
Collagen II, Mouse, mAb M2139 100 µg F FS IA P HM1063
Endostatin, Human, mAb 1837-46 100 µg F FC IA P W HM2188
FUS, Human, mAb LHC7.15 100 µg IF IP W HM2260
Phosphotyrosine, mAb P9V6 100 µg IA W HM5003
Spi-6, Mouse, pAb 100 µg FC W HP8035
TIM-4, Mouse, mAb Kat5-18 100 µg FC FS IA IF HM1111
Ubiquitin, mAb Ubi-1 100 µg F IA IF IP P W HM5009
 
For research purposes only. Not for drug, diagnostic or other use.

F Frozen sections
FC Flow cytometry
FS Functional studies
IA Immuno assays
IF Immuno fluorescence
IP Immuno precipitation
P Paraffin sections
W Western blot