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Coagulation description
Both pro- and anticoagulant pathways are involved in inflammation and in many inflammatory diseases. The protein C anticoagulant pathway serves as a major system for controlling thrombosis, limiting inflammatory responses, and potentially decreasing endothelial cell apoptosis in response to inflammatory cytokines. The essential components of this pathway include thrombin, thrombomodulin, the endothelial cell protein C receptor (EPCR), protein C and protein S. Life-threatening coagulation disorders, such as thrombotic thrombocytopenic purpura (TTP) often arise from deficiency or inhibition of the enzyme ADAMTS-13.
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Coagulation molecules » Coagulation
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Quantity
|
Application
|
Cat #
|
|
Protein C, Human, mAb PC107
|
|
100
µg
|
IA W
|
HM2151
|
|
ADAMTS-13, Human, mAb 20A5
|
|
100
µg
|
IA IF W
|
HM2226
|
|
ADAMTS-13, Human, mAb 5C11
|
|
100
µg
|
IA W
|
HM2225
|
|
EPCR, Human, mAb RCR-252
|
|
100
µg
|
FC FS IP W
|
HM2145
|
|
EPCR, Human, mAb RCR-379
|
|
100
µg
|
F FC FS
|
HM2144
|
|
PAI-1, Human, mAb MA-33H1F7
|
|
100
µg
|
FS IA W
|
HM2179
|
|
PAI-1, Human, mAb MA-55F4C12
|
|
100
µg
|
FS IA
|
HM2180
|
|
PAI-1, Human, mAb MA-56A7C10
|
|
100
µg
|
FS IA
|
HM2181
|
|
PAI-1, Rat, mAb MA-124K1
|
|
100
µg
|
FS IA
|
HM3026
|
|
Protein S, Human, mAb PS7
|
|
100
µg
|
FC W
|
HM2148
|
|
Protein S, Human, mAb PS7, FITC
|
|
100
µg
|
FC W
|
HM2148F
|
|
Punctin-1, Human, mAb 1B2-8-14
|
|
100
µg
|
IA W
|
HM2194
|
|
Punctin-1, Human, mAb 1B2-8-2
|
|
100
µg
|
IA W
|
HM2169
|
|
EPCR, Human, mAb RCR-252, FITC
|
|
100
µg
|
FC FS IP W
|
HM2145F
|
|
Thrombomodulin, Human, mAb RTM96
|
|
100
µg
|
FC FS W
|
HM2146
|
|
Thrombomodulin, Human, mAb RTM98
|
|
100
µg
|
FC W
|
HM2147
|
For research purposes only. Not
for drug, diagnostic or other use.
|
F
|
Frozen sections
|
|
FC
|
Flow cytometry
|
|
FS
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Functional studies
|
|
IA
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Immuno assays
|
|
IF
|
Immuno fluorescence
|
|
IP
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Immuno precipitation
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P
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Paraffin sections
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|
W
|
Western blot
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