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MBL, related proteins description
Mannose-Binding Lectin (MBL) also called mannan-binding lectin, mannose- or mannan-binding protein (MBP) is a member of the collectins and an important element in innate immunity. It forms a complex with C1r/C1s like serine proteases designated MASP that proteolytically cleave C4, C2 and C3. MBL is able to activate the complement pathway independent of the classical and alternative pathways. MBL exhibits complement-dependent anti-bacterial activity and acts directly as an opsonic and therefore plays an important role in innate immunity. MBL-deficiency has been related to a number of diseases. Measurement of functional MBL is of interest in studies on bacterial infections, autoimmune diseases, cancer, HIV, transplantation, atherosclerosis, cystic fibrosis, transplantation and many other diseases. HB offers antibodies and assays to human MBL, unique assays for mouse MBL-A and MBL-C, MASP2, and MBL/MASP2.
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Complement, Collectins » MBL, related proteins
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Quantity
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Application
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Cat #
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MBL, Human, ELISA kit
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1 x 96
det.
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HK323-01
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MBL, Human, mAb 3E7
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0.5
mg
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F FC IA W
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HM2061-IA
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MASP-2, Human, mAb 8B5
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0.5
mg
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IA W
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HM2190-IA
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MASP-2/MAp19, Human, mAb 6G12
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0.5
mg
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IA W
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HM2191-IA
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MASP-1/3, Human, mAb 1E2
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100
µg
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IA IP W
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HM2092
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MASP-1/3, Human, mAb 2B11
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100
µg
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IA IP W
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HM2093
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MASP-2, Human, ELISA kit
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2 x 96
det.
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HK326
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MASP-2, Human, mAb 8B5
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100
µg
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IA W
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HM2190
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MASP-2/MAp19, Human, mAb 6G12
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100
µg
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IA W
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HM2191
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MASP-3, Human, ELISA kit
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2 x 96
det.
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HK339
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MASP-3, Human, mAb 38:12-3
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100
µg
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IA W
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HM2216
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MBL, Human, ELISA kit
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2 x 96
det.
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HK323-02
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MBL, Human, mAb 3E7
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100
µg
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F FC IA W
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HM2061
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MBL, Human, mAb 3E7, FITC
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100
µg
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F FC IA W
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HM2061F
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MBL, Human, mAb D8.18
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100
µg
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FC IA W
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HM2081
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MBL, Human, mAb D8.18, biotinylated
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50
µg
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FC IA W
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HM2082
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MBL/MASP-2, Human, ELISA kit
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2 x 96
det.
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HK327
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MBL-A, Mouse, ELISA kit
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2 x 96
det.
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HK208
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MBL-A, Mouse, mAb 2B4
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100
µg
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IA W
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HM1036
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MBL-A, Mouse, mAb 8G6
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100
µg
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F IA IF W
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HM1035
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MBL-C, Mouse, ELISA kit
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2 x 96
det.
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HK209
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MBL-C, Mouse, mAb 14D12
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100
µg
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F IA IF W
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HM1038
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MBL-C, Mouse, mAb 16A8
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100
µg
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IA W
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HM1037
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For research purposes only. Not
for drug, diagnostic or other use.
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F
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Frozen sections
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FC
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Flow cytometry
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FS
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Functional studies
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IA
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Immuno assays
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IF
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Immuno fluorescence
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IP
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Immuno precipitation
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P
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Paraffin sections
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W
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Western blot
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