Adhesion molecules description

Adhesion molecules are proteins involved in the binding of cells either to other cells or to components of the extracellular matrix. In addition, adhesion molecules can participate in cell signaling or display enzymatic activities. For example, the oxidase activity of vascular adhesion protein-1 (VAP-1) controls leukocyte infiltration into tissues and induces endothelial E- and P-selectins. Cell junctions play an important role in cell-to-cell adhesion and cell barrier functions. Together with gap junctions and adherens junctions, tight junctions form apical junctional complexes in epithelial and endothelial cells. These junctions hold cells together and prevent the passage of molecules and ions through the intercellular space. Furthermore, they block the movement of integral membrane proteins between the apical and basolateral surfaces of the cell.

 
Adhesion molecules Quantity Application Cat #
CD34, Mouse, mAb MEC14.7 100 µg F FC IF IP P W HM1015
CD166, Human, mAb AZN-L50 0.5 mg F FC FS IF IP P W HM2002-FS
Alpha-V/Beta-3 Integrin, Human, mAb BV3, FITC 100 µg FC IA IF IP P HM2034F
CD56, Human, mAb NKI-nbl-1 100 µg F FC HM2133
FHL2, Human, mAb F4B2-B11 100 µg F IF P W HM2136
CD11/CD18, Human, mAb 24 100 µg F FC FS IA IP HM2183
AIF-1, Human, mAb 1022-5 100 µg IA P W HM2184
E-selectin, Human, mAb ENA1 0.5 mg F FS IA IP HM4001-IA
ICAM-1, Human, pAb, biotinylated 50 µg F IA IP W HP9018BT
HAKAI, Human, pAb 100 µg F IF W HP9038
alpha-5 Integrin (Fibronectin-receptor), Human, mAb NKI-SAM1 100 µg F FC HM2126
Alpha-Catenin, Human, mAb 1G5 100 µg FC IF IP W HM2118
Alpha-V/Beta-3 Integrin, Human, mAb BV3 100 µg FC IA IF IP P HM2034
Beta1 Integrin, Human, mAb BV7 100 µg FC FS IA IP W HM2033
Beta1 Integrin, Human, mAb BV7, FITC 100 µg FC IA W HM2033F
Beta-Catenin, Human, mAb 9F2 100 µg FC IF IP W HM2112
CD222, Human, mAb MEM-238 100 µg FC W HM2121
CD44, Human, mAb NKI-P2 100 µg F FC P HM2127
CD56, Human, mAb 123C3 100 µg F IF P HM2132
CD73, Human, mAb 4G4 100 µg F FC FS IF IP W HM2215
Endomucin, Mouse, mAb V.7C7.1 100 µg F FC IP P W HM1108
E-selectin, Human, mAb ENA1 100 µg F FS IA IP HM4001
E-selectin, Human, mAb ENA2 100 µg F FS IA HM4003
E-selectin, Human, pAb, biotinylated 50 µg F IA W HP9017
ICAM-1, Human, mAb HM.1 100 µg IA IF HM4004
ICAM-1, Human, mAb HM.1, biotinylated 50 µg IA IF HM4005
ICAM-1, Human, mAb HM.2 100 µg F FC IA IF IP P HM2104
ICAM-1, Human, mAb HM.2, biotinylated 50 µg F FC IA IF IP P HM2104BT
ICAM-1, Human, pAb, biotinylated 50 µg F IA IP W HP9018
IgG (H+L), Rabbit, pAb, FITC 1.5 mg F FC P HP1201
IgG (H+L), Rabbit, pAb, HRP 1.2 mg F IA P W HP1202
IgG (H+L), Rat, pAb, FITC 1.5 mg F FC P HP1101
IgG (H+L), Rat, pAb, HRP 1.2 mg F IA P W HP1102
IgG+IgM (H+L), Mouse, pAb, FITC 1.5 mg F FC P HP1001
IgG+IgM (H+L), Mouse, pAb, HRP 1.2 mg F IA P W HP1002
IgG1, Mouse, biotinylated 50 µg F FC P HI1002
IgG1, Mouse, FITC 50 µg FC HI1003
IgG1, Rat 50 µg F FC IA HI3001
IgG1, Rat, biotinylated 50 µg FC HI3002
IgG1, Rat, FITC 50 µg FC HI3003
IgG2a, Mouse 50 µg F FC P HI1004
IgG2a, Mouse, biotinylated 50 µg FC HI1005
IgG2a, Mouse, FITC 50 µg FC HI1006
IgG2a, Rat 50 µg F FC IA HI3004
IgG2a, Rat, biotinylated 50 µg FC HI3005
IgG2a, Rat, FITC 50 µg FC HI3006
IgG2b, Mouse 50 µg F FC P HI1007
IgG2b, Mouse, biotinylated 50 µg F FC P HI1008
IgG2b, Mouse, FITC 50 µg F FC P HI1009
IgG2b, Rat 50 µg FC HI3007
IgG2b, Rat, biotinylated 50 µg FC HI3008
IgG2b, Rat, FITC 50 µg FC HI3009
IgY, Chicken, mAb 7C2 100 µg IA IP W HM4009
IgY, Chicken, mAb 7C2, biotinylated 50 µg IA W HM4010
IgY, Chicken, mAb 7C2, HRP-conjugated 50 µg IA W HM4011
JAM-A, domain 1, Human, pAb 100 µg FC P W HP9041
JAM-A, domain 2, Human, pAb 100 µg FC P W HP9042
MAdCAM-1, Human, mAb 314G8 100 µg F FC FS IA P W HM2207
CD166, Human, mAb AZN-L50 100 µg F FC FS IF IP P W HM2002
Beta-3 integrin subunit, Human, mAb BV4 100 µg F FC IA IP P W HM2035
MAdCAM-1, Human, mAb 314G8, FITC 100 µg F FC FS IA P W HM2207F
PECAM-1, Human, mAb BV8 100 µg FC IA IP HM2039
PECAM-1, Mouse, mAb ER-MP12 100 µg F FC IA IP P HM1084
PECAM-1, Mouse, mAb MEC7.46 100 µg F FC IF IP HM1013
PECAM-1, Mouse, mAb MEC7.46, biotinylated 50 µg F FC IF IP HM1014
PECAM-1, Mouse, mAb MEC7.46, FITC 100 µg F FC IF IP HM1013F
sMAdCAM-1, Human, ELISA kit 2 x 96 det. HK337
VAP-1, Human, mAb 174-5 100 µg F FC FS IF HM2213
VAP-1, Mouse, mAb 7-88 100 µg F FC FS IF IP HM1094
VCAM-1, Human, mAb 1G11B1 100 µg F FC FS IA IP HM4006
VCAM-1, Human, mAb 1G11B1, biotinylated 50 µg F FC FS IA HM4007
VCAM-1, Mouse, mAb 6C7.1 100 µg F FC FS IF IP HM1107
VE-Cadherin, Human, mAb BV9 100 µg F FC FS IA IF IP W HM2032
VE-Cadherin, Human, mAb BV9, FITC 100 µg F FC FS IA IF IP W HM2032F
Vitronectin, Human, mAb BV1 100 µg FC IA IF IP W HM2036
JAM-A, Human, mAb M.Ab.F11 0.5 mg FC FS IF IP W HM2099-FS
Barmotin/7H6 antigen, Human, mAb 7H6 100 µg F W HM2102
GEF-H1, Human, mAb B4/7 100 µg F IF IP W HM2152
JAM-A, Human, mAb BV16 100 µg F FC IF W HM2098
JAM-A, Human, mAb BV16, FITC 100 µg F FC IF W HM2098F
JAM-A, Human, mAb M.Ab.F11 100 µg FC FS IA IF IP P W HM2099
JAM-A, Mouse, mAb BV12 100 µg FC IA IF HM1050
JAM-A, Mouse, mAb BV12, FITC 100 µg FC IA IF W HM1050F
JAM-C, Mouse, mAb CRAM-18F26 100 µg F FC FS IA IP HM1057
JAM-C, Mouse, mAb 19H36 100 µg F FC IA IP HM1056
L-Afadin, Rat, mAb 3 100 µg F IA IP W HM3013
Occludin, Human, pAb 100 µg F IF W HP9047
ZO-1, alpha-, Human, pAb 100 µg F IF P W HP9045
ZO-1, alpha+, Human, pAb 100 µg F FC IF P W HP9044
ZO-1, Human, pAb 100 µg FC IF W HP9043
ZO-2, Human, pAb 100 µg F IF W HP9046
Nectin-2, Mouse, mAb 502-57, FITC 100 µg F FC IA IP W HM1052F
Nectin-3, Mouse, mAb 103-A1, FITC 100 µg F FC FS IA IF IP HM1053F
Desmoglein-1, Human, mAb 27B2 100 µg F IF IP W HM2113
Desmoglein-2, Human, mAb 6D8 100 µg F IF IP W HM2114
Desmoglein-3, Human, mAb 5G11 100 µg IF IP P W HM2115
Nectin-2, Mouse, mAb 502-57 100 µg F FC IA IP W HM1052
Nectin-3, Mouse, mAb 103-A1 100 µg F FC FS IA IF IP HM1053
Plakoglobin, Human, mAb 15F11 100 µg IF IP W HM2116
 
For research purposes only. Not for drug, diagnostic or other use.

F Frozen sections
FC Flow cytometry
FS Functional studies
IA Immuno assays
IF Immuno fluorescence
IP Immuno precipitation
P Paraffin sections
W Western blot