Acute Phase proteins description

Acute phase proteins (APPs) are serum proteins whose levels change in response to inflammation, which makes them useful indicators for stress and disease. The functions of APPs remain largely unresolved. Nevertheless, various roles have been postulated, including opsonisation of foreign organisms and particles, and regulation of inflammatory processes. Examples of the latter are LPS-binding protein (LBP) and serum amyloid A (SAA), both involved in the inflammatory response to LPS. Elevation of C-reactive protein (CRP) levels relates to a number of diseases, including atherosclerosis, rheumatoid arthritis and sepsis, making this APP an important indicator of inflammation. Another well-characterized APP is mannose-binding lectin (MBL), which activates the lectin complement pathway and is therefore an important element in innate immunity.

 
Acute Phase proteins Quantity Application Cat #
SAA-1, Human, mAb Reu86.1 0.5 mg F IA P W HM2100-IA
SAA-1, Human, mAb Reu86.5 0.5 mg F IA P W HM2101-IA
PTX3, Human, mAb MNB1 0.5 mg F FS IA IP P W HM2241-FS
PTX3, Human, mAb MNB1 0.5 mg F FS IA IP P W HM2241-IA
PTX3, Human, mAb MNB4, FITC 100 µg F FC IA IF IP P W HM2242F
PTX3, Human, mAb MNB4 0.5 mg F FC IA IF IP P W HM2242-IA
Pentraxin 3, Human, ELISA kit 2 x 96 det. HK347
PTX3, Human, mAb MNB1 100 µg F FS IA IP P W HM2241
PTX3, Human, mAb MNB4 100 µg F FC IA IF IP P W HM2242
SAA, Human, ELISA kit 2 x 96 det. HK333
SAP, Human, ELISA kit 2 x 96 det. HK331
CRP, Human, ELISA kit 1 x 96 det. HK358
SAP, Mouse, pAb 100 µg F IA IP P W HP8039
SAP, Human, pAb 100 µg F IA IP P W HP9055
SAA-1, Human, mAb Reu86.1 100 µg F IA P W HM2100
SAA-1, Human, mAb Reu86.5 100 µg F IA P W HM2101
 
For research purposes only. Not for drug, diagnostic or other use.

F Frozen sections
FC Flow cytometry
FS Functional studies
IA Immuno assays
IF Immuno fluorescence
IP Immuno precipitation
P Paraffin sections
W Western blot