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Scavenger Receptors description
Scavenger receptors (SRs) are cell surface proteins that were studied initially for their ability to bind and internalize modified lipoproteins. However, different classes of these receptors are involved in host defense where they serve as pattern-recognition receptors (PRRs) for a wide variety of pathogens. Together with Toll-like receptors (TLRs), SRs are considered to be the most essential PRRs involved in atherosclerosis. Another set of important PRRs are the lectin-like molecules, proteins or glycoproteins that bind to specific sugar residues such as lycoconjugates present on cell surfaces. Lectinlike molecules serve many different biological functions like the regulation of cell adhesion, glycoprotein synthesis, and the control of protein levels in the blood.
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Scavenger Receptors
|
Quantity
|
Application
|
Cat #
|
|
Mannose receptor, Human, mAb 15-2
|
|
0.5
mg
|
F FC FS W
|
HM2056-FS
|
|
LOX-1, Human, mAb 23C11
|
|
0.5
mg
|
FC FS IF
|
HM2138-FS
|
|
MARCO, Human, mAb PLK-1
|
|
0.5
mg
|
F FC FS IF IP W
|
HM2208-FS
|
|
CD163, Human, mAb RM3/1
|
|
100
µg
|
F FC FS IF IP W
|
HM2157
|
|
CD163, Rat, mAb ED2
|
|
100
µg
|
F FC IP P
|
HM3025
|
|
CD205, Mouse, mAb NLDC-145
|
|
100
µg
|
F FC
|
HM1069
|
|
CD68, Human, mAb KP1
|
|
1
ml
|
F FC IP P W
|
HM2177
|
|
CD68, Mouse, mAb FA-11
|
|
100
µg
|
F FC IF IP W
|
HM1070
|
|
CD68, Rat, mAb ED1
|
|
100
µg
|
F FC IP P W
|
HM3029
|
|
DC-SIGN, Human, mAb DCN47.5
|
|
100
µg
|
FC FS
|
HM2209
|
|
DC-SIGN, Human, mAb DCN47.5, biotinylated
|
|
50
µg
|
FC
|
HM2209BT
|
|
DC-SIGN, Human, mAb DCN47.5, FITC
|
|
100
µg
|
FC
|
HM2209F
|
|
Dectin-1, Mouse, mAb 2A11
|
|
100
µg
|
F FC FS IP
|
HM1067
|
|
Galectin-3, Human, mAb B2C10
|
|
100
µg
|
F FC FS IA P W
|
HM2186
|
|
LOX-1, Human, mAb 23C11
|
|
100
µg
|
FC FS IF
|
HM2138
|
|
LOX-1, Human, mAb 23C11, biotinylated
|
|
50
µg
|
FC FS IF
|
HM2138BT
|
|
LOX-1, Human, mAb 23C11, FITC
|
|
100
µg
|
FC FS IF
|
HM2138F
|
|
Mannose receptor, Human, mAb 15-2
|
|
100
µg
|
F FC FS W
|
HM2056
|
|
SR-A, Mouse, mAb 2F8
|
|
100
µg
|
F FC FS IP W
|
HM1061
|
|
Mannose receptor, Human, mAb 15-2, biotinylated
|
|
50
µg
|
F FC FS W
|
HM2057
|
|
Mannose receptor, Mouse, mAb MR5D3
|
|
100
µg
|
F FC FS IA IF IP W
|
HM1049
|
|
MARCO, Human, mAb PLK-1
|
|
100
µg
|
F FC FS IF IP W
|
HM2208
|
|
MARCO, Mouse, mAb ED31
|
|
100
µg
|
F FC FS IP
|
HM1068
|
|
MGL, Mouse, mAb ER-MP23
|
|
100
µg
|
F FC FS
|
HM1081
|
|
SI-CLP, Human, mAb 1C11
|
|
100
µg
|
IF W
|
HM2240
|
|
Siglec-H, Mouse, mAb 440c
|
|
100
µg
|
F FC FS
|
HM1075
|
|
Siglec-H, Mouse, mAb 440c, biotinylated
|
|
50
µg
|
F FC
|
HM1095
|
|
Siglec-H, Mouse, mAb 440c, FITC
|
|
100
µg
|
F FC
|
HM1075F
|
|
SIGN-R1, Mouse, mAb ER-TR9
|
|
>200
µg
|
F FC FS
|
HM1080
|
|
SR-BI, Rat, mAb 3D12
|
|
100
µg
|
F FC FS
|
HM3027
|
|
TREM-1, Mouse, mAb L5-B8
|
|
100
µg
|
FC FS IF W
|
HM1098
|
For research purposes only. Not
for drug, diagnostic or other use.
|
F
|
Frozen sections
|
|
FC
|
Flow cytometry
|
|
FS
|
Functional studies
|
|
IA
|
Immuno assays
|
|
IF
|
Immuno fluorescence
|
|
IP
|
Immuno precipitation
|
|
P
|
Paraffin sections
|
|
W
|
Western blot
|