Toll Like Receptors - Hycult® Biotech

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Toll Like Receptors description

Toll like receptors (TLRs) are a class of non-catalytic receptors that function as pattern recognition receptors (PRRs). These receptors recognize pathogen-associated molecular patterns (PAMPs) that are shared by large groups of microorganisms, but also endogenous alarm signals, like apoptosis related membrane fragments and inflammatory ligands. Common cytoplasmic domains allow TLRs to use the same signaling molecules used by the interleukin-1 receptors (IL-1Rs), including MyD88 and TRIF. In man both intracellular and extracellular TLR exist. The intracellularly located TLR9 confers responses to bacterial DNA via species-specific CpG-motif recognition. Therefore, CpG-DNA can be used to investigate TLR9 response in various systems.

Toll Like Receptors	Quantity	Application	Cat #
CpG-A DNA (ODN 2216), Human/Mouse	200 nmol		HC4037
CpG-B DNA (ODN 2006), Human/ Mouse	200 nmol		HC4039
CpG-B DNA, Rabbit	200 nmol		HC4038
CpG-B DNA, Rat	200 nmol		HC4040
CpG-C DNA (ODN 2395), Human/ Mouse	200 nmol		HC4041
CpG-DNA, Mouse	200 nmol		HC4033
Non CpG-DNA, Human/Mouse	200 nmol		HC4034
Non CpG-DNA, Rabbit	200 nmol		HC4042
TLR4/MD-2, Mouse, mAb MTS510	0.5 mg	F FC FS IP	HM1029-FS
CD180, Mouse, mAb RP/14	100 µg	FC FS	HM1031
CD180, Mouse, mAb RP/14, biotinylated	100 µg	FC	HM1032
CD180, Mouse, mAb RP/14, FITC	100 µg	FC	HM1031F
MD-1, Mouse, mAb MD113	100 µg	FC FS	HM1040
MD-1, Mouse, mAb MD113, biotinylated	50 µg	FC	HM1041
MD-1, Mouse, mAb MD113, FITC	100 µg	FC	HM1040F
TLR2, Mouse, mAb 6C2	100 µg	FC IF IP	HM1047
TLR2, Mouse, mAb 6C2, biotinylated	50 µg	FC	HM1048
TLR2, Mouse, mAb 6C2, FITC	100 µg	FC IF	HM1047F
TLR 2, Mouse, mAb 6C2, R-PE labeled	100 tests	FC IF IP	HM1047PE-100
TLR2, Mouse, mAb 6C2, R-PE labeled	25 tests	FC IF IP	HM1047PE-25
TLR2, Mouse, mAb mT2.7, R-PE labeled	100 tests	F FC IP P	HM1058PE-100
TLR2, Mouse, mAb mT2.7, R-PE labeled	25 tests	F FC IP P	HM1058PE-25
TLR2, Mouse, mAb mT2.4	100 µg	F FC FS IA P	HM1092
TLR2, Mouse, mAb mT2.4, biotinylated	50 µg	F FC IA P	HM1092BT
TLR2, Mouse, mAb mT2.7	100 µg	F FC IP P	HM1058
TLR2, Mouse, mAb mT2.7, biotinylated	50 µg	F FC	HM1059
TLR2, Mouse, mAb mT2.7, FITC	100 µg	F FC IA	HM1058F
TLR2, Mouse, mAb T2.5	100 µg	F FC FS IA IF IP	HM1054
TLR2, Mouse, mAb T2.5, biotinylated	50 µg	F FC FS IA IF IP	HM1055
TLR2, Mouse, mAb T2.5, FITC	100 µg	F FC FS IA IF IP	HM1054F
TLR2, Mouse, pAb	50 µg	FC W	HP8016
TLR4/MD-2, Mouse, mAb MTS510	100 µg	F FC FS IP	HM1029
TLR4/MD-2, Mouse, mAb MTS510, biotinylated	50 µg	F FC FS IP	HM1030
TLR4/MD-2, Mouse, mAb MTS510, FITC	100 µg	F FC FS IP	HM1029F
TLR9, Mouse, mAb 5G5	100 µg	F FC IA P W	HM1042
TLR9, Mouse, mAb 5G5, biotinylated	50 µg	F FC IA W	HM1043
TLR9, Mouse, mAb 5G5, FITC	100 µg	F FC IA P W	HM1042F
TLR2, Human, mAb T2.5	0.5 mg	F FC FS IA IF IP	HM1054-FS
TLR2, Human, mAb TL2.1	0.5 mg	F FC FS IF IP P W	HM2064-FS
TLR2, Human, mAb TL2.1, PE	100 tests	F FC FS IF IP P W	HM2064PE-100
TLR2, Human, mAb TL2.1, PE	25 tests	F FC FS IF IP P W	HM2064PE-25
TLR2, Human, mAb TL2.3, PE	100 tests	FC IA W	HM2066PE-100
TLR2, Human, mAb TL2.3, PE	25 tests	FC IA W	HM2066PE-25
TLR4, Human, mAb HTA125, PE	100 tests	FC FS IA IF IP W	HM2068PE-100
TLR4, Human, mAb HTA125, PE	25 tests	FC FS IA IF IP W	HM2068PE-25
TLR1, Human, mAb GD2.F4, PE	100 tests	F FC FS IA IF P	HM2085PE-100
TLR1, Human, mAb GD2.F4, PE	25 tests	F FC FS IA IF P	HM2085PE-25
TLR3, Human, mAb TLR3.7	0.5 mg	F FC FS IF IP P W	HM2096-FS
TLR6, Human, mAb TLR6.127, PE	100 tests	FC FS IF IP P	HM2221PE-100
TLR6, Human, mAb TLR6.127, PE	25 tests	FC FS IF IP P	HM2221PE-25
MD-2, Human, mAb 18H10	100 µg	FC FS	HM2245
TLR4/MD-2, Human, mAb 7E3	0.5 mg	FC FS	HM2246-FS
CD180, Human, mAb MHR73	100 µg	F FC FS IP P	HM2083
CD180, Human, mAb MHR73, biotinylated	50 µg	F FC	HM2084
CD180, Human, mAb MHR73, FITC	100 µg	F FC FS IP	HM2083F
sMD-2 and sMD-2/TLR4, Human, mAb 4H1	100 µg	FS IA IF W	HM2243
TLR4, Human, mAb 3C3, biotinylated	50 µg	FC	HM2247BT
TLR2, Human, mAb TL2.1	100 µg	F FC FS IF IP P W	HM2064
TLR2, Human, mAb TL2.1, biotinylated	50 µg	F FC FS IF IP P W	HM2065
TLR2, Human, mAb TL2.1, FITC	100 µg	F FC P W	HM2064F
TLR2, Human, mAb TL2.3	100 µg	FC IA W	HM2066
TLR2, Human, mAb TL2.3, biotinylated	50 µg	FC IA W	HM2067
TLR2, Human, mAb TL2.3, FITC	100 µg	F FC IA IF W	HM2066F
TLR2, Human, mAb TLR2.45, FITC	100 µg	IF	HM2220F
TLR2, Human, mAb TLR2.45	100 µg	IF	HM2220
TLR2, Human, mAb TLR2.45, biotinylated	50 µg	IF	HM2220BT
TLR3, Human, mAb TLR3.7	100 µg	F FC FS IF IP P W	HM2096
TLR3, Human, mAb TLR3.7, biotinylated	50 µg	F FC FS IF IP P W	HM2097
TLR3, Human, mAb TLR3.7, FITC	100 µg	F FC FS IF IP P W	HM2096F
TLR4, Human, mAb 3C3	100 µg	FC FS	HM2247
TLR4, Human, mAb 3C3, FITC	100 µg	FC	HM2247F
TLR4, Human, mAb HTA125	100 µg	FC FS IA IF IP W	HM2068
TLR2, Human, mAb T2.5	100 µg	F FC FS IA IF IP	HM1054
TLR4, Human, mAb HTA125, biotinylated	50 µg	FC FS IA IF IP W	HM2069
TLR1, Human, mAb GD2.F4	100 µg	F FC FS IA IF P	HM2085
TLR1, Human, mAb GD2.F4, FITC	100 µg	F FC FS IA IF P	HM2085F
TLR1, Human, mAb GD2.F4, biotinylated	100 µg	F FC FS IA IF P	HM2086
sMD-2 and sMD-2/TLR4, Human, mAb 4H1, FITC	100 µg	FS IA IF W	HM2243F
MD-2, Human, mAb 18H10, biotinylated	50 µg		HM2245BT
MD-2, Human, mAb 18H10, FITC	100 µg	FC FS	HM2245F
TLR4, Human, mAb HTA125, FITC	100 µg	FC FS IA IF IP W	HM2068F
TLR4/MD-2, Human, mAb 7E3	100 µg	FC FS	HM2246
TLR4/MD-2, Human, mAb 7E3, biotinylated	50 µg	FC	HM2246BT
TLR4/MD-2, Human, mAb 7E3, FITC	100 µg	FC	HM2246F
TLR5, Human, mAb 19D759.2	100 µg	F FC IF P W	HM2159
TLR5, Human, mAb 19D759.2	100 µg	F FC IF P W	HM2159F
TLR6, Human, mAb TLR6.127	100 µg	FC FS IF IP P	HM2221
TLR6, Human, mAb TLR6.127, biotinylated	50 µg	IF	HM2221BT
TLR6, Human, mAb TLR6.127, FITC	100 µg	IF	HM2221F
TLR7, Human, pAb	100 µg	F FC IF IP W	HP9040
TLR8, Human, mAb 44C143	100 µg	FC IF P W	HM2160
TLR8, Human, mAb 44C143, FITC	100 µg	FC IF P W	HM2160F
TLR9, Human, mAb 5G5	100 µg	F FC IA IF P W	HM2087
TLR9, Human, mAb 5G5, biotinylated	50 µg	F FC IA IF P W	HM2088
TLR9, Human, mAb 5G5, FITC	100 µg	F FC IA IF P W	HM2087F

For research purposes only. Not for drug, diagnostic or other use.

F	Frozen sections
FC	Flow cytometry
FS	Functional studies
IA	Immuno assays

IF	Immuno fluorescence
IP	Immuno precipitation
P	Paraffin sections
W	Western blot