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CD36 description

CD36 (88-kDa) is a cell surface class B scavenger receptor, also known as thrombospondin receptor. CD36 has been identified as a protein that is required for TLR2 recognition of di-acylated bacterial lipopeptides and lipoteichoic acid. CD36 is a heavily N-glycosylated transmembrane protein of 90 kDa with two short intracellular domains and a large extracellular domain. CD36 expression is primarily controlled by the transcription heterodimer PPARg-RXR (peroxisome proliferator-activated receptor-g-retinoid-X-receptor). CD36 is preferentially found within lipid rafts, which facilitates its association with receptors, signalling and adaptor molecules. CD36 is expressed on platelets, mature monocytes and macrophages, microvascular endothelial cells, mammary endothelial cells, during stages of erythroid cell development and on some macrophage derived dendritic cells. CD36 has been implicated in many biological processes including angiogenesis, phagocytosis, inflammation, and lipid and glucose metabolism.

 
Lipid-binding proteins » CD36 Quantity Application Cat #
CD36, Human, mAb FA6-152 0.5 mg F FC FS IA IF IP HM2122-FS
CD36, Rat, mAb UA009 0.5 mg F FC FS IA IP HM3019-FS
CD36, Human, mAb FA6-152 100 µg F FC FS IA IF IP HM2122
CD36, Human, mAb FA6-152, biotinylated 50 µg F FC FS IA IF IP HM2122BT
CD36, Human, mAb FA6-152, FITC 100 µg F FC FS IA IF IP HM2122F
CD36, Mouse, mAb CRF D2712 200 µg FC FS IF IP W HM1074
CD36, Rat, mAb UA009 100 µg F FC FS IA IP HM3019
 
For research purposes only. Not for drug, diagnostic or other use.

F Frozen sections
FC Flow cytometry
FS Functional studies
IA Immuno assays
IF Immuno fluorescence
IP Immuno precipitation
P Paraffin sections
W Western blot