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HNP1-3 and BPI: markers of Childhood Obesity

Monday, April 25, 2016

Short Summary of Prats-Puig, A et al; α-Defensins and bacterial/permeability-increasing protein as new markers of childhood obesity. Ped Obesity 2016

Associations of circulating α-defensins and bacterial/permeability increasing protein with metabolic and vascular parameters have been previously described in adults. In our cross-sectional study, we have found that α-defensins are related to a poorer metabolic profile during childhood.

Findings indicate that α-defensins and bacterial/permeability-increasing protein are related to obesity parameters and cardiovascular risk markers in children. α-Defensins could be novel markers of BMI and abdominal fat deposition in children.

 

Correlation graphs of α-defensins at ~7 years with A) Body mass index (BMI) z-score and B) waist at follow-up in the children included in the longitudinal study.



Posted in Scientific Publications By

Kim Peeters