Toll like receptors, mouse - Hycult® Biotech

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Toll like receptors, mouse description

Toll like receptors (TLRs) are a class of non-catalytic receptors that function as patternrecognition receptors (PRRs). These receptors recognize pathogen-associated molecular patterns (PAMPs) that are shared by large groups of microorganisms, but also endogenous alarm signals, like apoptosis related membrane fragments and inflammatory ligands. Common cytoplasmic domains allow TLRs to use the same signaling molecules used by the interleukin-1 receptors (IL-1Rs), including MyD88 and TRIF. In man both intracellular and extracellular TLR exist. The intracellularly located TLR9 confers responses to bacterial DNA via species-specific CpG-motif recognition. Therefore, CpG-DNA can be used to investigate TLR9 response in various systems.

Toll Like Receptors » Toll like receptors, mouse	Quantity	Application	Cat #
TLR4/MD-2, Mouse, mAb MTS510	0.5 mg	F FC FS IP	HM1029-FS
CD180, Mouse, mAb RP/14	100 µg	FC FS	HM1031
CD180, Mouse, mAb RP/14, biotinylated	100 µg	FC	HM1032
CD180, Mouse, mAb RP/14, FITC	100 µg	FC	HM1031F
MD-1, Mouse, mAb MD113	100 µg	FC FS	HM1040
MD-1, Mouse, mAb MD113, biotinylated	50 µg	FC	HM1041
MD-1, Mouse, mAb MD113, FITC	100 µg	FC	HM1040F
TLR2, Mouse, mAb 6C2	100 µg	FC IF IP	HM1047
TLR2, Mouse, mAb 6C2, biotinylated	50 µg	FC	HM1048
TLR2, Mouse, mAb 6C2, FITC	100 µg	FC IF	HM1047F
TLR 2, Mouse, mAb 6C2, R-PE labeled	100 tests	FC IF IP	HM1047PE-100
TLR2, Mouse, mAb 6C2, R-PE labeled	25 tests	FC IF IP	HM1047PE-25
TLR2, Mouse, mAb mT2.7, R-PE labeled	100 tests	F FC IP P	HM1058PE-100
TLR2, Mouse, mAb mT2.7, R-PE labeled	25 tests	F FC IP P	HM1058PE-25
TLR2, Mouse, mAb mT2.4	100 µg	F FC FS IA P	HM1092
TLR2, Mouse, mAb mT2.4, biotinylated	50 µg	F FC IA P	HM1092BT
TLR2, Mouse, mAb mT2.7	100 µg	F FC IP P	HM1058
TLR2, Mouse, mAb mT2.7, biotinylated	50 µg	F FC	HM1059
TLR2, Mouse, mAb mT2.7, FITC	100 µg	F FC IA	HM1058F
TLR2, Mouse, mAb T2.5	100 µg	F FC FS IA IF IP	HM1054
TLR2, Mouse, mAb T2.5, biotinylated	50 µg	F FC FS IA IF IP	HM1055
TLR2, Mouse, mAb T2.5, FITC	100 µg	F FC FS IA IF IP	HM1054F
TLR2, Mouse, pAb	50 µg	FC W	HP8016
TLR4/MD-2, Mouse, mAb MTS510	100 µg	F FC FS IP	HM1029
TLR4/MD-2, Mouse, mAb MTS510, biotinylated	50 µg	F FC FS IP	HM1030
TLR4/MD-2, Mouse, mAb MTS510, FITC	100 µg	F FC FS IP	HM1029F
TLR9, Mouse, mAb 5G5	100 µg	F FC IA P W	HM1042
TLR9, Mouse, mAb 5G5, biotinylated	50 µg	F FC IA W	HM1043
TLR9, Mouse, mAb 5G5, FITC	100 µg	F FC IA P W	HM1042F

For research purposes only. Not for drug, diagnostic or other use.

F	Frozen sections
FC	Flow cytometry
FS	Functional studies
IA	Immuno assays

IF	Immuno fluorescence
IP	Immuno precipitation
P	Paraffin sections
W	Western blot