Home \ Antibodies \ Ficolin-2, Human, mAb GN4, biotinylated
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Catalog # HM2090BT-50UG

Ficolin-2, Human, mAb GN4, biotinylated

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The monoclonal antibody GN4 recognizes human Ficolin-2, also known as L-ficolin. Ficolins are a family of pattern recognition molecules containing both a collagen-like domain and a fibrinogen-like domain that are capable of activating the complement system, through association with MASPs, on the surface of microorganisms. In human, three Ficolins are known: Ficolin-1 (M-ficolin), Ficolin-2 (L-ficolin), and Ficolin-3 (H-ficolin). Ficolin-1, is mainly expressed by monocytes, granulocytes and lung cells and is present locally in areas of inflammation.
Ficolin-2 (also L-ficolin, ficolin L, EBP-37 or hucolin) is produced primarily by the liver. The association between Ficolin-2 and MASPs/sMAP is Ca2+-dependent. MASPs in Ficolin-2-MASP complexes have proteolytic activities for C4, C2 and C3. Ficolin-2 also shows opsonic activity.

Application
Frozen sections, Immuno assays, Immuno precipitation

Product type
Monoclonal antibodies
Amount
50 µg
Formulation
0.5 ml (100 µg/ml) 0.2 µm filtered antibody solution in PBS, containing 0.02% sodium azide and 0.1% bovine serum albumin.
Conjugate
Biotin
Isotype
Mouse IgG1
Species
Human
Storage and stability
Product should be stored at 4°C. Under recommended storage conditions, product is stable for one year.
Precautions
For research use only. Not for use in or on humans or animals or for diagnostics. It is the responsibility of the user to comply with all local/state and Federal rules in the use of this product. Hycult Biotech is not responsible for any patent infringements that might result with the use of or derivation of this product.
Disease
Cardiology and metabolism, Infectious diseases
Protocol
Protocol Sandwich ELISA
49 kb
Protocol Immuno precipitation
54 kb
CoA-TDS HM1067-HM2099
HM2090BT-50UG
113 kb
Safety Data Sheet
SDS - HM2090BT-50UG
52 kb

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