Home \ Antibodies \ LPLUNC1, Mouse, pAb
Catalog # HP8044

LPLUNC1, Mouse, pAb

120,00462,00

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The polyclonal antibody recognizes mouse LPLUNC1 (Long palate, lung and nasal epithelium clone 1). LPLUNC1, also known as BPI fold-containing family member B1 (BPIFB1), is a protein present in the trachea, the epithelium and submucosal glands of larger airways and some smaller airways. It is also found in minor mucosal glands of the nasal cavity and more abundantly in minor, compared with major, salivary glands. Currently, the function of LPLUNC is unknown. It may be involved in the innate immune
response to bacterial exposure in the mouth, nasal cavities, and lungs. Recently, a significant association between a specific LPLUNC1 SNP (single nucleotide polymorphism), located in the promoter region of the gene, and susceptibility to infection by the cholera-causing bacterium Vibrio cholera has been identified. However, its precise role in susceptibility to infection and/or the development of disease needs to be further elucidated.

Application
Immuno fluorescence, Paraffin sections, Western blot

Application Notes
W: A reduced sample treatment and SDS-Page was used. The band size is 50 kDa (Ref.2).
IHC-P: Tissue sections were pretreated with tri-sodium citrate buffer for 8 minutes in a microwave oven followed by rinsing in PBS. Tissue sections were fixed in 3 % H2O2 in methanol for 20 minutes (Ref.1)

Use
For Western blotting, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50. For functional studies, in vitro dilutions have to be optimized in user’s experimental setting.

Positive Control
Nasopharyngeal tissues

Product type
Polyclonal antibodies
Quantity
20 µg, 100 µg
Formulation
0.2 ml (100 µg/ml) 0.2 µm filtered antibody solution in PBS, containing 0.1% bovine serum albumin and 0.02% sodium azide.
Isotype
Rabbit Ig
Species
Mouse
Storage and stability
Product should be stored at 4°C. Under recommended storage conditions, product is stable for at least - one year. The exact expiry date is indicated on the label.
Precautions
For research use only. Not for use in or on humans or animals or for diagnostics. It is the responsibility of the user to comply with all local/state and federal rules in the use of this product. Hycult Biotech is not responsible for any patent infringements that might result from the use or derivation of this product.
Disease
Pulmonology, Tumor immunology
Protocol CoA-TDS pAb
HP8044
177 kb

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