Home \ Antibodies \ Plakoglobin, Human, mAb 15F11
Catalog # HM2116

Plakoglobin, Human, mAb 15F11

Read more
Please choose the quantity of items you wish to add to your cart…
Find distributor

Plakoglobin, also known as gamma-catenin belongs together with alpha- and beta catenin to the catenin family. Catenins mediates cell-cell adhesion by interaction with cadherins. Plakoglobin is found in desmosomes and adherens junctions. Plakoglobin is highly homologous to beta-catenin although its function differs from that of beta-catenin. Whereas beta-catenin has been found in potentiating hyperproliferation and tumor formation, plakoglobin can suppress tumorigenicity. Overexpression of plakoglobin has been shown to suppress cell proliferation and cell tumorigenicity in animals. Furthermore reduced plakoglobin expression has been found in tumor tissues and metastatic lesions of renal cells, esophageal carcinomas and in skin carcinomas. The monoclonal antibody 15F11 cross reacts with rat and weakly with mouse.

Application
Immuno fluorescence, Immuno precipitation, Western blot

Use
For Western blotting and immunofluorescence dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:10.

Product type
Monoclonal antibodies
Amount
100 µg, 20 µg
Formulation
0.2 ml (100 µg/ml) 0.2 µm filtered antibody solution in PBS, containing 0.02% sodium azide and 0.1% bovine serum albumin.
Isotype
Mouse IgG1
Species
Human
Cross reactivity
Mouse – Weak, Rat – Yes
Storage and stability
Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.
Precautions
For research use only. Not for use in or on humans or animals or for diagnostics. It is the responsibility of the user to comply with all local/state and Federal rules in the use of this product. Hycult Biotech is not responsible for any patent infringements that might result with the use of or derivation of this product.
Disease
Cardiology and metabolism
Protocol
Protocol Western Blot
59 kb
Protocol SDS Page
57 kb
Protocol Immuno precipitation
54 kb
Protocol Immuno Fluorescence
39 kb
CoA-TDS HM2100-HM2199
HM2116-100UG
75 kb
HM2116-20UG
76 kb
Safety Data Sheet
SDS - HM2116-100UG
52 kb
SDS - HM2116-20UG
52 kb

Related products

Calculate your ELISA data easily

With the ELISA calculator you can easily calculate ELISA data. Assayfit Pro helps to perform curve fitting. The calculator generates advanced reports, fit graph, fit parameters and goodness of fit are shown.

Show data entry
Find distributor - Prices