IFN-beta, Mouse, Recombinant (CHO-derived)

Catalog #: HC1050-01
Quantity: 5 x 10E4 units
$529.00

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Description
Details
Three types of interferons have been described: interferon-alpha (IFN-alpha), interferon-beta (IFN-beta), and interferon-gamma (IFN-gamma). An extensive variety of biological effects have been observed for the interferon family including antiviral activity; anti-proliferative activity; stimulation of cytotoxic activities in lymphocytes, natural killer cells, and macrophages; and modulation of the major histocompatibility complex. Only one mouse-IFN-beta gene has yet been described. It codes for a 161 amino acid polypeptide (20 kD). Mouse-IFN-beta binds to the type I interferon receptor. It is not recognized by antibodies directed against mouse alpha interferon or mouse gamma interferon. One unit of mouse beta interferon is the amount of beta interferon which protects 50% of the indicator cell population from viral destruction. One unit of Hycult Biotech Mouse Beta Interferon approximates the bioactivity contained in one unit of the mouse beta interferon standard prepared by NIH (Gb02-902-511).
Specifications

Specifications

Catalog number HC1050-01
Product type Proteins
Quantity 5 x 10E4 units
Species Mouse
Formulation Lyophilized product in PBS, 100 µm mouse albumin and 0.1% gelatin containing 5.0 x 10E4 Units. Reconstitute the vial by injection of 1 ml distilled or de-ionized water (Caution: vial is under vacuum).
Storage and stability Lyophilized product should be stored at 4°C. Store stock solution after reconstitution in aliquots at -20°C. Note: mouse IFN-beta is highly labile when agitated. Repeated freeze and thaw cycles and prolonged exposure to light will cause loss of activity. Under recommended storage conditions, product is stable for one year.
Precautions For research use only. Not for use in or on humans or animals or for diagnostics. It is the responsibility of the user to comply with all local/state and Federal rules in the use of this product. Hycult Biotech is not responsible for any patent infringements that might result with the use of or derivation of this product.
Disease Autoimmunity, Infectious diseases
Application
References
References
References:
1. De Maeyer, E et al; Interferons and Other Regulatory Cytokines, 1st ed., 1988, Wiley and Sons, New York
2. Vonk, W et al; Large-scale, one-step purification of murine interferon-beta using a monoclonal antibody. J Interferon Res 1983, 3: 169
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