Alpha-5 Integrin (Fibronectin-receptor), Human, mAb NKI-SAM1

Catalog #: HM2126
Quantity: 100 µg
$384.00

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Description
Details
Fibronectin receptor, also designated VLA-5, is a 130/150 kDa protein. The protein functions as a receptor for fibronectin and mediates binding of B and T lymphocytes to fibronectin. Fibronectin is an extracellular matrix glycoprotein that functions in cell adhesion and migration in wound healing, embryonic development and malignant transformation. The fibronectin receptor is expressed on monocytes and monocytoid cell lines, leukocytes, memory T cells, fibroblasts, platelets and muscle cells.
Specifications

Specifications

Catalog number HM2126
Product type Monoclonal antibodies
Quantity 100 µg
Formulation 1 ml (100 µg/ml) 0.2 µm filtered antibody solution in PBS, containing 0.02% sodium azide and 0.1% bovine serum albumin.
Isotype Mouse IgG2b
Species Human
Storage and stability Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.
Precautions For research use only. Not for use in or on humans or animals or for diagnostics. It is the responsibility of the user to comply with all local/state and Federal rules in the use of this product. Hycult Biotech is not responsible for any patent infringements that might result with the use of or derivation of this product.
Disease Cardiology and metabolism
Application
Applications
  • Application:
    F, FC
  • Use:
    For immunohistology and flow cytometry dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:10.
References
References
References:
1. te Velde, A et al; Modulation of phenotypic and functional properties of human peripheral blood monocytes by IL-4. J Immunol 1988, 140: 1548
2. Danen, E et al; Requirement for the synergy site for cell adhesion to fibronectin depends on the activation state of Integrin alpha(5)beta(1). Americ. Soc for Biochem and Mol Biol 1995, 270: 21612
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