TLR and inflammasome

Toll like receptors (TLRs) are a class of non-catalytic receptors that function as pattern recognition receptors (PRRs). These receptors recognize pathogen-associated molecular patterns (PAMPs) that are shared by large groups of microorganisms, but also endogenous alarm signals, like apoptosis related membrane fragments and inflammatory ligands. Common cytoplasmic domains allow TLRs to use the same signaling molecules used by the interleukin-1 receptors (IL-1Rs), including MyD88 and TRIF. In man both intracellular and extracellular TLR exist. The intracellularly located TLR9 confers responses to bacterial DNA via species-specific CpG-motif recognition. Therefore, CpG-DNA can be used to investigate TLR9 response in various systems.
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Product description Price Quantity Applications Catalog #  
TLR4/MD-2, Mouse, mAb MTS510
$330.00
100 µg F FC FS IF IP HM1029

TLR4/MD-2, Mouse, mAb MTS510, FITC
$398.00
100 µg F FC FS IF IP HM1029F

TLR4/MD-2, Mouse, mAb MTS510,functional study antibody, low endotoxin
$1,068.00
0.5 mg F FC FS IF IP HM1029-FS

TLR4/MD-2, Mouse, mAb MTS510, biotinylated
$251.00
50 µg F FC FS IP HM1030

CD180, Mouse, mAb RP/14
$330.00
100 µg FC FS HM1031

MD-1, Mouse, mAb MD113
$330.00
100 µg FC FS IF HM1040

Mannose receptor, Mouse, mAb MR5D3
$477.00
100 µg F FC FS IA IF IP W HM1049

TLR2, Mouse/Human, mAb T2.5
$464.00
100 µg F FC FS IA IF IP HM1054

TLR2, Mouse/Human, mAb T2.5, FITC
$398.00
100 µg F FC FS IA IF IP HM1054F

TLR2, Mouse/Human, mAb T2.5, functional study antibody, low endotoxin
$1,068.00
0.5 mg F FC FS IA IF IP HM1054-FS

CD14, Mouse, mAb Sa14-2
$422.00
100 µg FC FS IF IP W HM1060

CD14, Mouse, mAb Sa14-2, FITC
$529.00
100 µg FC FS IF HM1060F

CD14, Mouse, mAb Sa14-2, functional study antibody, low endotoxin
$1,213.00
0.5 mg FC FS IF IP W HM1060-FS

TLR2, Mouse, mAb mT2.4
$330.00
100 µg F FC FS IA P HM1092

Mannose receptor, Human, mAb 15-2
$477.00
100 µg F FC FS W HM2056

Mannose receptor, Human, mAb 15-2, functional study antibody, low endotoxin
$1,345.00
0.5 mg F FC FS W HM2056-FS

Mannose receptor, Human, mAb 15-2, biotinylated
$398.00
50 µg F FC FS W HM2057

TLR2, Human, mAb TL2.1
$330.00
100 µg F FC FS IF IP P W HM2064

TLR2, Human, mAb TL2.1, FITC
$398.00
100 µg F FC FS IF IP P W HM2064F

TLR2, Human, mAb TL2.1, functional study antibody, low endotoxin
$1,068.00
0.5 mg F FC FS IF IP P W HM2064-FS

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Abbreviation legend
  • F Frozen sections
  • IF Immuno fluorescence
  • FC Flow cytometry
  • IP Immuno precipitation
  • FS Functional studies
  • P Paraffin sections
  • IA Immuno assays
  • W Western blot
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