Acute phase proteins

Acute phase proteins (APPs) are serum proteins whose levels change in response to inflammation, which makes them useful indicators for stress and disease. The functions of APPs remain largely unresolved. Nevertheless, various roles have been postulated, including opsonization of foreign organisms and particles, and regulation of inflammatory processes. Examples of the latter are LPS-binding protein (LBP) and serum amyloid A (SAA), both involved in the inflammatory response to LPS. Elevation of C-reactive protein (CRP) levels relates to a number of diseases, including atherosclerosis, rheumatoid arthritis and sepsis, making this APP an important indicator of inflammation. Another well-characterized APP is mannose-binding lectin (MBL), which activates the lectin complement pathway and is therefore an important element in innate immunity.
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  1. PTX3, Human, mAb MNB4, FITC
    20 µg
    FC F IA IF IP P W
    HM2242F-20UG
  2. SAP, Human, pAb
    20 µg
    F IA IP P W
    HP9055-20UG
  3. LBP, Human, pAb
    20 µg
    IA IP W
    HP9023-20UG
  4. BPI, Human, pAb
    20 µg
    IA IP
    HP9022-20UG
  5. SAP, Mouse, pAb
    20 µg
    F IA IP P W
    HP8039-20UG
  6. sTREM-1, Human, mAb 15G7
    20 µg
    IA
    HM2304-20UG
  7. TREM-1, Human, mAb 6B1
    20 µg
    FC FS IA W
    HM2252-20UG
  8. PTX3, Human, mAb MNB4
    20 µg
    FC F IA IF IP P W
    HM2242-20UG
  9. PTX3, Human, mAb MNB1
    20 µg
    FC FS IA W
    HM2241-20UG
  10. SAA-1, Human, mAb Reu86.5
    20 µg
    F IA P W
    HM2101-20UG
  11. SAA-1, Human, mAb Reu86.1
    20 µg
    F IA P W
    HM2100-20UG
  12. LBP, Human, mAb 1C7
    20 µg
    FS IA IP
    HM2044-20UG
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Abbreviation legend

F Frozen sections
FC Flow cytometry
FS Functional studies
IA Immuno assays
IF Immuno fluorescence
IP Immuno precipitation
P Paraffin sections
W Western blot

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