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Complement and collectins
The complement system consists of a number of small proteins found in the blood, in general synthesized by the liver, and normally circulating as inactive precursors (pro-proteins). When stimulated by one of several triggers, proteases in the system cleave specific proteins to release cytokines and initiate an amplifying cascade of further cleavages. Complement activation further assists in opsonization, triggering and clearance of pathogens. Over 30 proteins and protein fragments make up the complement system, including serum proteins, serosal proteins, and cell membrane receptors. They account for about 10% of the globulin fraction of blood serum.
Three biochemical pathways activate the complement system: the classical complement pathway, the alternative complement pathway, and the lectin pathway.
Product description
Quantity
Applications
Catalog #
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2 x 96 det.HK211-02
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2 x 96 det.HK356-02
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100 µgF FS IA IF IP PHM1073
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10 mgF FS IA IF IP PHM1073-10B
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5 mgF FS IA IF IP PHM1073-5B
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0.5 mgF FS IA IF IP PHM1073-FS
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100 µgF FS IA IF WHM1096
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50 µgF FS IA IF WHM1096BT
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100 µgF FS IA IF WHM1096F
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100 µgF FC IA IF WHM1118
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100 µgF IA WHM1119
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100 µgF IA WHM1119F
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100 µgFC FS IA IP P WHM2014
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100 µgFC FS IA IP P WHM2014F
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100 µgFC FS IA IF IP WHM2015
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0.5 mgFC FS IA IP WHM2015-FS
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100 µgF IA IP WHM2091
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0.5 mgF IA IP WHM2091-IA
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1 x 96 det.HK356-01
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1 x 96 det.HK211-01
Abbreviation legend
F Frozen sections
FC Flow cytometry
FS Functional studies
IA Immuno assays
IF Immuno fluorescence
IP Immuno precipitation
P Paraffin sections
W Western blot
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