TIGIT, Mouse, clone TX99

Quantity:
100 µg
Catalog #:
HM1149-100UG

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Specifications
Product type Monoclonal antibodies
Quantity 100 µg
Formulation 0.2 µm filtered in PBS+0.1%BSA
Application Flow cytometry, Functional studies
Use Dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50.
Immunogen Recombinant protein
Isotype Rat IgG1
Species Mouse
References Nakamura, Y et al; TX99 Is a Neutralizing Monoclonal Antibody Against Mouse TIGIT. Mon ab in Immunodiagnosis and immunotherapy, 2018, 37:105
Storage and stability Product should be stored at 4°C. Under recommended storage conditions, product is stable for at least one year.
Precautions For research use only. Not for use in or on humans or animals or for diagnostics. It is the responsibility of the user to comply with all local/state and federal rules in the use of this product. Hycult Biotech is not responsible for any patent infringements that might result from the use or derivation of this product.
Applications
Application: Flow cytometry, Functional studies
Application notes: - FC: An extracellular protocol was used. With Ba/F3 cells the shift is ~10-12%
- FS: TX99 is a neutralizing mAb that can be used for studies of mTIGIT functions: TX99 interfered with the interaction between TIGIT and CD155 and increased NK cell-mediated cytotoxicity against CD155-expressing RMA-S cells. (Ref. 1).
Use: Dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50.
References
References: Nakamura, Y et al; TX99 Is a Neutralizing Monoclonal Antibody Against Mouse TIGIT. Mon ab in Immunodiagnosis and immunotherapy, 2018, 37:105
CoA-TDS HM1067-HM2099
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