A-FABP, Human, pAb

Catalog #: HP9028
Quantity: 100 µg
$464.00

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Description
Details
The polyclonal antibody recognizes human adipocyte fatty acid binding protein (A-FABP) of both natural and recombinant origin. The A-FABP protein is derived from the human FABP4 gene. FABPs are small intracellular proteins (~13-14 kDa) with a high degree of tissue specificity that bind long chain fatty acids. They are abundantly present in various cell types and play an important role in the intracellular utilization of fatty acids, transport and metabolism. There are at least nine distinct types of FABP, each showing a specific pattern of tissue expression. Due to its small size, FABP leaks rapidly out of ischemically damaged necrotic cells leading to a rise in serum levels. Ischemically damaged tissues are characterized histologically by absence (or low presence) of FABP facilitating recognition of such areas. A-FABP is localized in the adipose tissue.
Specifications

Specifications

Catalog number HP9028
Product type Polyclonal antibodies
Quantity 100 µg
Formulation 1 ml (100 µg/ml) 0.2 µm filtered antibody solution in PBS, containing 0.1% bovine serum albumin and 0.02% sodium azide.
Isotype Rabbit Ig
Species Human
Cross reactivity Rat - Yes
Alias FABP4, Adipocyte lipid binding protein, ALBP, aP2
Storage and stability Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.
Precautions For research use only. Not for use in or on humans or animals or for diagnostics. It is the responsibility of the user to comply with all local/state and federal rules in the use of this product. Hycult Biotech is not responsible for any patent infringements that might result with the use or derivation of this product.
Disease Cardiology and metabolism
Application
Applications
  • Application:
    IA, W
  • Use:
    For Western blotting, dilution to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50.
References
References
References:
1. Veerkamp, J et al; Cytoplasmic fatty acid-binding proteins: their structure and genes. Prog Lipid Res 1995, 34: 17
2. Veerkamp, J et al; Stuctural and functional studies on different human FABP types. Mol Cell Biochem 1999, 192: 137
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