IL-6, Mouse, mAb MP5-32C11
The antibody neutralizes mouse interleukin 6 (IL-6). It does not cross-react with LPS (the component of the
bacterial cell wall which is considered responsible for the toxicity of gram-negative bacteria) and TNFalpha
nor does it block human or rat IL-6 in proliferation assays using the KD83 cell line. MP5-32C11
inhibits mouse IL-6-induced proliferation of the NFS60 myelomonocytic cell line and KD83 plasmacytoma.
IL-6 is a pluripotent 20-22 kDa cytokine which plays a role in the pathophysiology of severe infection and
regulates the immune response, acute phase reaction and haematopoiesis. IL-6 plays a critical role in Bcell
differentiation to plasma cells and is a potent growth factor for plasmacytoma and myeloma.
Continuous IL-6 gene expression makes an essential contribution to a multistep oncogenesis of plasma
cell neoplasia. IL-6 is a very useful culture supplement for the generation of a high number of antibodyproducing
hybridomas.
Calculate your ELISA data easily
With the ELISA calculator you can easily calculate ELISA data. Assayfit Pro helps to perform curve fitting. The calculator generates advanced reports, fit graph, fit parameters and goodness of fit are shown.
Latest Hycult Biotech news
- New Human Complement Pathway AssaysWe are very proud of our newly developed human classical and alternative complement pathway assays. They are produced in response to a growing demand for quantitative investigation of complement inhibitors or regulators at lower sample dilutions. This development aims to address the issue of false negative results, enabling more accurate and reliable analysis of complement… Read more: New Human Complement Pathway Assays
- Navigating the pitfalls in complement analysisOur colleague Erik Toonen shared his experience on how to analyze complement at the Complement-based Drug Development Summit in Boston in September 11-13th, 2023. He showed valuable insights on analyzing complements. For accurate complement analysis, it is important that not only the correct technique is used but also that pre-analytical sample handling is performed in… Read more: Navigating the pitfalls in complement analysis
- NEW Human C3d ELISAWe are happy to introduce our new ELISA (cat.# HK3017) designed to detect human C3d. What sets this assay apart is its utilization of a distinctive neo-epitope capture antibody that selectively targets a specific C3d region of the alpha chain, which is not available in other C3 variants. This way it specifically distinguishes C3d from native C3… Read more: NEW Human C3d ELISA