RBC, Mouse, mAb 34-3C

Name: RBC, Mouse, mAb 34-3C
SKU: HM1120
Availability: InStock

€133.00 – €1,245.00

Please choose the quantity of items you wish to add to your cart…

Amount

Quantity:

Add to basket

Description
Application

The monoclonal antibody 34-3C recognizes an exposed surface determinant of intact red blood cells (RBC). The high-affinity anti-RBC monoclonal antibody efficiently bind to Fc receptors on macrophages inducing anemia in vivo due to a rapid Fc receptor (FcyR)-mediated erythrophagocytosis of opsonised RBC in spleen and livers. The capacity of the antibody to interact with FcyR is responsible for its haemolytic activity. The monoclonal antibody only recognises antigenic determinants expressed on Mouse RBC and not on other species of RBC.

Application

Flow cytometry, Functional studies

Use

For flow cytometry dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50. For functional studies, in vitro dilutions have to be optimized in user's experimental setting.

Positive Control

Mouse erythrocytes

Specifications
Downloads

Product type

Monoclonal antibodies

Amount

100 µg, 20 µg, 500 µg

Formulation

Quantities >500 µg will be send without preservative and carrier free. Quantities <500 µg will be send with preservative and carrier. exact formulation can be found on the datasheet.

Immunogen

RBC

Isotype

Mouse IgG2a

Species

Mouse

Cross reactivity

Chicken – No, Human – No, Rabbit – No, Rat – No, Sheep – No

Storage and stability

Product should be stored at 4 °C. Under recommended storage conditions, product is stable for at least one year. The exact expiry date is indicated on the label.

Precautions

For research use only. Not for use in or on humans or animals or for diagnostics. It is the responsibility of the user to comply with all local/state and federal rules in the use of this product. Hycult Biotech is not responsible for any patent infringements that might result from the use or derivation of this product.

Disease

Autoimmunity, Infectious diseases

Protocol