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Catalog # HK3001

MASP-1/C1-INH, ELISA

Human MASP-1/C1-INH Complex ELISA is a ready-to-use solid-phase enzyme-linked immunosorbent assay based on the sandwich principle with a working time of 1 hour and 45 minutes.

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810,001.308,00

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Investigate and unravel early complement activation in complement-mediated diseases

Complement-mediated inflammation is linked to a wide variety of diseases. In some cases, it is important to intervene as early as possible in this process as it has direct clinical implications. Currently C1-INH administration in its natural or recombinant form is an approved treatment for hereditary angioedema (HAE).

C1-INH or other early complement inhibitors are investigated for better targeted therapies in pending clinical studies. Hence the C1-INH complexes can be used as an indirect marker for ongoing classical or lectin pathway activation.

Why looking at C1-INH and its complexes?

C1-INH administration is an approved common treatment for hereditary angioedema (HAE) and in clinical trials for:

– Covid-19 infections

– Prevention of rejection in kidney transplantation

– Traumatic brain injury and acute ischemic stroke

– Endotoxemia, sepsis, inflammation and multiple organ failure

– Application in end stage renal disease and chronic kidney disease

The key advantages:

– Ready-to-use ELISA’s with a working time of 1 hour and 45 minutes

– Acute and reliable quantification of MASP-1/C1-INH complex

– Uses EDTA-plasma as input sample. No need for complement-preserved serum to assess early lectin pathway activation

– First on the market available ELISA assay to measure early classical and early lectin pathway activation

Documents:

> Read the manual for more information

> Read the safety data sheet

Application
The Human MASP-1/C1-INH Complex ELISA kit is to be used for the in vitro quantitative determination of MASP-1/C1-INH Complex in plasma and serum samples

Principle
The Human MASP-1/C1-INH Complex ELISA is a ready-to-use solid-phase enzyme-linked immunosorbent assay based on the sandwich principle with a working time of 1 hour and 45 minutes.

Product type
Assays
Quantity
1 x 96 det., 2 x 96 det.
Standard range
0.39 to 25 ng/ml
Detection level
0.39 ng/ml
Working volume
100 µl/well
Species
Human
Cross reactivity
Dog – No, Horse – No, Mouse – No, Pig – No, Rat – No
Storage and stability
Product should be stored at 4 °C. Under recommended storage conditions, product is stable for at least six months.
Precautions
For research use only. Not for use in or on humans or animals or for diagnostics. It is the responsibility of the user to comply with all local/state and Federal rules in the use of this product. Hycult Biotech is not responsible for any patent infringements that might result with the use of or derivation of this product.
Assay Manual
HK3001
394 kb
Safety Data Sheet

Calculate your ELISA data easily

With the ELISA calculator you can easily calculate ELISA data. Assayfit Pro helps to perform curve fitting. The calculator generates advanced reports, fit graph, fit parameters and goodness of fit are shown.

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