Home \ Assays \ C1s/C1-INH, Human, ELISA
EDN, Human, ELISA kit-0
EDN, Human, ELISA kit-0
Catalog # HK399

C1s/C1-INH, Human, ELISA

The C1-INH/C1s complex plays a pivotal role in the complement system, an essential component of the innate immune defense against infections.

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The C1s/C1-INH complex actively controls the complement system’s classical pathway, crucial for the body’s innate immune defense against infections. This complex forms when C1 inhibitor (C1-INH) binds with C1r and C1s, effectively regulating the proteolysis-based activation cascade and preventing overreaction of the immune system. In diseases like Hereditary Angioedema (HAE) and Systemic Lupus Erythematosus (SLE), the altered levels of the C1s/C1-INH complex provide key insights into immune activity, establishing its importance as a biomarker for monitoring immune responses.

Application
The Human C1s/C1-INH Complex ELISA kit is to be used for the in vitro quantitative determination of C1s/C1-INH Complex in plasma and serum samples

Principle
The Human C1s/C1-INH Complex ELISA is a ready-to-use solid-phase enzyme-linked immunosorbent assay based on the sandwich principle with a working time of 1 hour and 45 minutes.

Product type
Assays
Amount
1 x 96 det., 2 x 96 det.
Standard range
1.56 to 100 ng/ml
Detection level
1.56 ng/ml
Working volume
100 µl/well
Cross reactivity
Mouse – Yes
Storage and stability
Product should be stored at 4 °C. Under recommended storage conditions, product is stable for at least six months.
Precautions
For research use only. Not for use in or on humans or animals or for diagnostics. It is the responsibility of the user to comply with all local/state and Federal rules in the use of this product. Hycult Biotech is not responsible for any patent infringements that might result with the use of or derivation of this product.
Disease
Autoimmunity, Infectious diseases, Nephrology, Neurological disorders
Assay Manual
HK399
395 kb
Safety Data Sheet
SDS - HK399
61 kb
Flyer
Flyer C1sC1-INH and MASP-1C1-INH complex assays
52 kb

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