C1s/C1-INH Complex, Human, ELISA kit

The C1s/C1-INH complex actively controls the complement system’s classical pathway, crucial for the body’s innate immune defense against infections. This complex forms when C1 inhibitor (C1-INH) binds with C1r and C1s, effectively regulating the proteolysis-based activation cascade and preventing overreaction of the immune system. In diseases like Hereditary Angioedema (HAE) and Systemic Lupus Erythematosus (SLE), the altered levels of the C1s/C1-INH complex provide key insights into immune activity, establishing its importance as a biomarker for monitoring immune responses.