Catalog # HM2327
SUMO-1, Human, mAb 1B12-E2
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Find distributor Post-translational modification regulated by conjugation of a small ubiquitin-like modifier (SUMO) is involved in various cellular processes such as transcriptional regulation, apoptosis and nuclear transport. Recent proteomic analyses in mammalian cells revealed that a number of SUMO substrates and specific modifications by SUMO-1 are involved in essential processes, including chromatin organization, transcription, RNA metabolism, immunomodulation and development of the innate immune system.
Application
Immuno assays, Paraffin sections, Western blot
Application Notes
Higher expression of SUMO-1 was detected in normal adrenal gland, esophagus, pancreas, liver, stomach, kidney, and uterus. the function of SUMO-1 may vary depending on the tissue types.
IHC-P: Tissue sections were deparaffinized in xylene, rehydrated, and treated with fresh 0.3% hydrogen peroxide in methanol for 15 min.
W: A non-reduced sample treatment was used.
Use
For Western blotting, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:10.
Product type
Monoclonal antibodies
Amount
100 µg, 20 µg
Formulation
0.2 ml (100 µg/ml) 0.2 µm filtered antibody solution in PBS, containing 0.1% bovine serum albumin and 0.02% sodium azide.
Immunogen
hSUMO-1 and Lipoplex (O) complex
Isotype
Mouse IgG3
Species
Human
Alias
SMT3, GMP1, UBL1 and PIC1
Storage and stability
Product should be stored at 4°C. Under recommended storage conditions, product is stable for at least one year. The exact expiry date is indicated on the label.
Precautions
For research use only. Not for use in or on humans or animals or for diagnostics. It is the responsibility of the user to comply with all local/state and federal rules in the use of this product. Hycult Biotech is not responsible for any patent infringements that might result from the use or derivation of this product.
Disease
Cardiology and metabolism
Protocol
CoA-TDS HM2300-HM2400
Safety Data Sheet
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