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Catalog # HM1022

IL-1RI, Mouse, mAb Reg21

125.00390.00

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The monoclonal antibody binds to soluble mouse interleukin-1 receptor type I. The IL-1 system includes two agonists (IL-1alpha and IL-1beta), converting enzymes, antagonists, two receptors (IL-1RI and IL-1RII) and the IL-1 receptor accessory protein. Interleukin-1 signal is transduced through the type I receptor.

Application
Functional studies, Immuno assays

Application Notes
The antibody can be used for immuno assays and purification. Furthermore the antibody is useful for inhibition in biological assays, in vitro as well as in vivo.

Use
Dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:10. For neutralization of biological activity dilutions have to be made according to the amounts IL-1RI to be inactivated.

Product type
Monoclonal antibodies
Amount
100 µg, 20 µg
Formulation
0.2 ml (100 µg/ml) 0.2 µm filtered protein G purified antibody solution in PBS, containing 0.1% bovine serum albumin.
Isotype
Rat IgG1
Species
Mouse
Storage and stability
Product should be stored at 4°C. Under recommended storage conditions, product is stable for one year.
Precautions
For research use only. Not for use in or on humans or animals or for diagnostics. It is the responsibility of the user to comply with all local/state and Federal rules in the use of this product. Hycult Biotech is not responsible for any patent infringements that might result with the use of or derivation of this product.
Disease
Autoimmunity, Neurological disorders

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