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Catalog # HM2128

Keratin 7, Human, mAb OVTL 12/30


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Keratins are cytoplasmic intermediate filament proteins expressed by epithelial cells. Keratin 7 (K7) is expressed in a wide range of epithelial structures in humans. K7 occurs in the columnar and glandular epithelium of the lung, cervix, breast, in bile ducts, collecting ducts in the kidney and in mesothelium, but is absent in gastrointestinal epithelium, hepatocytes, proximal and distal tubules of the kidney and myoepithelium. The antibody OVTL 12/30 is an excellent tool in the differential diagnosis of malignant cells and to determine primary tumor localization. It stains a 54 kD protein band of cytoskeletal proteins from cell lines in one and two dimensional immunoblots.

Paraffin sections, Western blot

For immunohistology and Western blotting dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:10.

Product type
Monoclonal antibodies
100 µg, 20 µg
0.2 ml (100 µg/ml) 0.2 µm filtered antibody solution in PBS, containing 0.02% sodium azide and 0.1% bovine serum albumin.
Mouse IgG1
Storage and stability
Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.
For research use only. Not for use in or on humans or animals or for diagnostics. It is the responsibility of the user to comply with all local/state and Federal rules in the use of this product. Hycult Biotech is not responsible for any patent infringements that might result with the use of or derivation of this product.
Tumor immunology
Protocol CoA-TDS HM2100-HM2199 Safety Data Sheet

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