Product News

  1. Increased window of detection: EHEC results now possible up to two months after infection!

    The EcHECk ELISA enables reliable detection of IgM antibodies against EHEC bacteria in serum up to two months after onset of infection. Detection of EHEC is currently performed by PCR or culturing and these methods are not able to identify EHEC after one week of infection. Using this ELISA kit to determine a possible EHEC infection will offer you a Read more...
  2. Complement Poster

    Have you already requested a copy of the Hycult Biotech Complement Poster? Read more...
  3. Introducing: Two new Calprotectin ELISA kits!

    Two new Calprotectin ELISA's have been released for quantitative determination of Calprotectin: HK382 & HK379.

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  4. New! Mouse Complement Pathway Assays!

    The activation of the lectin complement pathways in mice can now be measured with the new Hycult Biotech Assays HIT420 and HIT421. Mouse Classical Complement Pathway Assay (HIT420) Mouse Lectin Complemement Pathway Assay (HIT421) The innate immune system is important in the first defense against foreign pathogens. A major component of Read more...
  5. Activation of granulocytes, hallmark for acute inflammation, sepsis and allergic conditions.

    Basophils, eosinophils and neutrophils are the three cell types that belong to the granulocytes. Granulocytes are a type of white blood cells characterized by the presence of granules in their cytoplasm. The nucleus shaped into the usual three lobes are typical for a granulocyte. They are released by bone marrow under the influence of complement through a process called granulopoiesis. Activation of granulocytes play a central role in the pathogenesis of many autoimmune diseases and are an important clinical hallmark for acute inflammation, sepsis and allergic conditions. Granulocytes form the first line of defense to many pathogens by releasing antimicrobial peptide.

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  6. Why do you need a gut barrier?

    The intestinal barrier is a functional entity separating the gut lumen from the inner host, and consisting of mechanical elements (mucus, epithelial layer), humoral elements (defensins, IgA), immunological elements (lymphocytes, innate immune cells), muscular and neurological elements.Intestinal permeability is a functional feature of the intestinal barrier function.

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  7. Serum TRACP isoform 5a as a potential risk marker in cardiovascular disease

    Tartrate-resistant acid phosphatase (TRACP) is a biomarker with multiple clinical and basic applications. It has long been used as a cytochemical marker to identify hairy cell leukemia cells and as a marker for differentiated cells of monocyte lineage including macrophages (MΦ), osteoclasts (OC), and dendritic cells (DC).

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  8. CML- a biomarker of general oxidative stress

    Carboxymethyl-lysine (CML) is a well-characterized glycoxidation product  that accumulates in tissues with age, and its rate of accumulation is accelerated in diabetes.

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  9. C3c as a stable complement biomarker

    The disadvantage of most complement biomarkers is their short half-life, making reliable sample collection and measurements difficult. Unlike other C3 fragments, C3c does not bind to other structures, like pathogens, cell surface (receptors) and other plasma proteins. Therefore, C3c is a stable complement biomarker which will appear in the fluid phase only, without interference of other C3 based products.

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  10. Enterocyte damage assessed by serum I-FABP in Celiac disease

    Celiac disease is an immune reaction to eating gluten, a protein found in wheat, barley and rye. Eating gluten triggers an immune response in the small intestine.

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