IL-1RI, Mouse, mAb Reg20
Quantity:
100 µg
Catalog #:
HM1023-100UG
The monoclonal antibody binds to soluble mouse interleukin-1 receptor type I. The IL-1 system includes two agonists (IL-1alpha and IL-1beta), converting enzymes, antagonists, two receptors (IL-1RI and IL-1RII) and the IL-1 receptor accessory protein. Interleukin-1 signal is transduced through the type I receptor.
| Product type | Monoclonal antibodies |
|---|---|
| Quantity | 100 µg |
| Formulation | 1 ml (100 µg/ml) 0.2 µm filtered antibody solution in PBS, containing 0.02% sodium azide and 0.1% bovine serum albumin. |
| Application | Immuno assays, Immuno precipitation, Western blot |
| Use | For Western blotting dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:10. |
| Isotype | Rat IgG2a |
| Species | Mouse |
| References | 1. Kojouharoff, G et al; Neutralization of tumour necrosis factor (TNF) but not of IL-1 reduces inflammation in chronic dextran sulphate sodium induced colitis in mice. Clin Exp Immunol 1997, 107: 353 2. Stern, A et al; Purification to homogeneity and amino acid sequence analysis of a receptor protein for interleu- kin-1. Arch Biochem Biophys 1989, 274: 26 |
| Storage and stability | Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year. |
| Precautions | For research use only. Not for use in or on humans or animals or for diagnostics. It is the responsibility of the user to comply with all local/state and Federal rules in the use of this product. Hycult Biotech is not responsible for any patent infringements that might result with the use of or derivation of this product. |
| Disease | Autoimmunity, Neurological disorders |
| Application: | Immuno assays, Immuno precipitation, Western blot |
|---|---|
| Application notes: | The antibody can be used for immuno assays, Western blotting, immuno precipitation and purification. |
| Use: | For Western blotting dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:10. |
| References: | 1. Kojouharoff, G et al; Neutralization of tumour necrosis factor (TNF) but not of IL-1 reduces inflammation in chronic dextran sulphate sodium induced colitis in mice. Clin Exp Immunol 1997, 107: 353 2. Stern, A et al; Purification to homogeneity and amino acid sequence analysis of a receptor protein for interleu- kin-1. Arch Biochem Biophys 1989, 274: 26 |
|---|
CoA-TDS HM1000-HM1066
Protocol
