Complement research in drug development

Bridging complement biology from discovery to therapy

The development of complement-targeting therapeutics requires a clear and reliable path from discovery to preclinical decision-making. A key challenge is translating results from animal studies into data that are robust, reproducible, and truly relevant for human drug development.

Generate translationally relevant complement data

Hycult Biotech offers validated complement assays that enable confident assessment of complement activation and inhibition throughout preclinical development. By generating high-quality data early, these tools support optimized study design and informed go/no-go decisions.

Improve efficiency in preclinical complement research

Well-designed ex vivo complement activation assays, including serum-based approaches, help focus in vivo studies on where they add the most value while minimizing repetitive experimentation. This results in more efficient preclinical programs, stronger human relevance, and improved outcomes driven by better data.

Assays for mouse and rat enabling confident preclinical decisions

Our functional pathway assays and sC5b-9 measurements are designed to perform reliably across species and development stages. Product selection includes scientific alignment to ensure assays match the intended application, supporting reliable translation from preclinical research toward clinical development.

ELISA kits for mouse
  • Mouse C1q (Cat.#HK211)
  • Mouse C3 (Cat.#HK2002)
  • Mouse C3b (Cat.#HK216)
  • Mouse C4 (Cat.#HK217)
  • Mouse Alternative pathway (Cat.#HIT422)
  • Mouse Classical pathway (Cat.#HIT420)
  • Mouse Lectin pathway (Cat.#HIT421)
  • Mouse Complement pathway collection (Cat.#HIT423)
ELISA kits for rat
  • Rat Alternative pathway (Cat.#HIT412)
  • Rat Classical pathway (Cat.#HIT410)
  • Rat Lectin pathway (Cat.#HIT411)
  • Rat Complement pathway collection (Cat.#HIT413)
  • Rat TCC (Cat.#HK106)
ELISA kits for pig
  • Pig Alternative pathway (Cat.#HIT432)
  • Pig Classical pathway (Cat.#HIT430)
  • Pig Lectin pathway (Cat.#HIT431)
  • Pig Complement pathway collection (Cat.#HIT433)

Expert Guidance in Assay Selection and Study Design

Hycult Biotech combines in-depth knowledge of the complement system with extensive expertise in assay development and validation. We actively support researchers in selecting the most appropriate assays for their specific research questions, ensuring that experimental strategies are scientifically sound, efficient, and translatable. By aligning assay choice with study objectives and regulatory expectations, Hycult helps maximize data quality while minimizing unnecessary in vivo experimentation.

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Hycult Biotech