Home \ Antibodies \ DNAM-1, Mouse, mAb TX92
Flow cytometric detection of DNAM-1 in mouse splenocytes. Red, blue and black line represent IgG2b Isotype control, splenocytes stained with DNAM-1 clone TX92 and unstained splenocytes respectively.
Flow cytometric detection of DNAM-1 in mouse splenocytes. Red, blue and black line represent IgG2b Isotype control, splenocytes stained with DNAM-1 clone TX92 and unstained splenocytes respectively.
DNAM-1, Mouse, mAb TX92 -1041
Flow cytometric detection of DNAM-1 in mouse splenocytes. Red, blue and black line represent IgG2b Isotype control, splenocytes stained with DNAM-1 clone TX92 and unstained splenocytes respectively.Flow cytometric detection of DNAM-1 in mouse splenocytes. Red, blue and black line represent IgG2b Isotype control, splenocytes stained with DNAM-1 clone TX92 and unstained splenocytes respectively.DNAM-1, Mouse, mAb TX92 -1041
Catalog # HM1137

DNAM-1, Mouse, mAb TX92

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€125.00 – €347.00

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DNAX accessory molecule-1 (DNAM-1) is a 65 kDa type I transmembrane glycoprotein and a member of the immunoglobulin superfamily. DNAM-1 is constitutively expressed on a majority of T cells, NK cells and macrophages. Interaction of DNAM-1 with DNAM-1 ligands CD155 and CD112 induces intercellular adhesion, infiltration and cell signaling, resulting in a variety of cellular responses including innate and adaptive immunities.

Application
Flow cytometry, Functional studies

Application Notes
FC: Antibody TX92 stains the extracellular domain of DNAM-1. FS: Antibody TX92 has an inhibitory function of DNAM-1 binding to the ligands. It additionally causes partial depletion of PB CD8+ T cells (Ref.1).

Use
For flow cytometry, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:25. For functional studies, in vitro dilutions have to be optimized in user’s experimental setting.

Product type
Monoclonal antibodies
Amount
100 µg, 20 µg
Formulation
0.2 ml (100 µg/ml) 0.2 µm filtered antibody solution in PBS, containing 0.1% bovine serum albumin.
Immunogen
BW5417 transfectant expressing mouse DNAM-1, boosted with DNAM-1-fc fusion protein.
Isotype
Rat IgG2b
Species
Mouse
Alias
DNAX accessory molecule-1, Cluster of Differentiation 226, PTA1
Storage and stability
Product should be stored at 4°C. Under recommended storage conditions, product is stable for at least one year. The exact expiry date is indicated on the label.
Precautions
For research use only. Not for use in or on humans or animals or for diagnostics. It is the responsibility of the user to comply with all local/state and federal rules in the use of this product. Hycult Biotech is not responsible for any patent infringements that might result from the use or derivation of this product.
Disease
Autoimmunity, Tumor immunology
Gene
Gene ID 225825 Uniprot Q5DW69
CoA-TDS HM1067-HM2099
HM1137-100UG
84 kb
HM1137-20UG
84 kb
HM1137F-100UG
84 kb
HM1137F-20UG
84 kb
Safety Data Sheet
SDS - HM1137-100UG
51 kb
SDS - HM1137-20UG
51 kb

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